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KMID : 0438419970040010035
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Korean Journal of Bone Metabolism
1997 Volume.4 No. 1 p.35 ~ p.41
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Effects of Alcohol Intake on Biochemical Bone Markers in Korean Adult Male
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Cho Jung-Sook
Kim Mi-Sun
Chung Yoon-Sok
Baik In-Kyung
Lee Duck-Joo
Lee Kwan-Woo
Kim Hyun-Man
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Abstract
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Efferts of alcohol intake on biochemical bone markers were investigated in 110 Korean healthy male subjects(age 25-65 years). Serum total alkaline phosphatase (TAP), bone alkaline phosphatase(BALP)and procollagen type I cerboxy-terminal propeptide(PICP) concentrations measured as bone formation markers, and type I collagen carboxy-terminal telopeptide(ICTP) concentration measured as bone resorption marker. There were significant correlations among serum TALP, BALP, and PICP concentrations(p<0.01). Current alcohol intake(g/day) was negatively correlated with TALP(r=0.19, p<0.05) and PICP concentrations(r=0.19, p<0.05) significantly. The current alcohol drinkers had lower serum TALP and BALP concentrations than non-drinkers. These results suggest that alcohol intake may have a suppressive effect on bone formation.
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KEYWORD
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Male subjects, Alcohol intake, Biochemical bone markers
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